Gene therapy using gene fusion for genetic or acquired...

Details Gene therapy using gene fusion for genetic or acquired... Gene therapy using gene fusion for genetic or acquired...

C - Chemistry, Metallurgy

12

N

167/202, 195/1.1

C12N 15/61 (2006.01) A61K 48/00 (2006.01) C07K 14/705 (2006.01) C07K 19/00 (2006.01) C12N 9/78 (2006.01) C12N 15/62 (2006.01) C12N 15/85 (2006.01)

Patent

CA 1339654

The present invention is related generally to the construction of fusion genes. More particularly, the present invention is related to the construction of a fusion gene comprising a coding sequence for a selectable marker linked by fusion to another coding sequence, the product of which is desired to be expressed in recipient cells. Gene therapy utilizing an MDR1 linked fusion coding sequence has been disclosed. Adenosine deaminase activity has been introduced into cells using MDR1 linked fusion gene.

601635

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