C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/25 (2006.01) A61K 48/00 (2006.01) C12N 15/85 (2006.01) C12N 15/86 (2006.01) A61K 38/19 (2006.01) C07K 14/545 (2006.01) C07K 14/715 (2006.01) C12N 15/24 (2006.01) C12N 5/06 (2006.01)
Patent
CA 2157782
The subject invention concerns a method of introducing at least one gene encoding a product into at least one cell of a connective tissue of a mammalian host for use in treating the mammalian host including employing recombinant to produce a DNA vector molecule which contains the gene encoding for the product and infecting the connective cell of the mammalian host using the DNA vector molecule using the gene coding for the product. A method is provided for introducing at least one gene encoding a product into at least one cell of a connective tissue of a mammalian host employing non-viral means. A method to produce an animal model for the study of connective tissue pathology is also disclosed. Additionally, this invention provides a method of using in vivo a gene encoding an extracellular interleukin-1 binding domain of an interleukin-1 receptor.
Evans Christopher H.
Glorioso Joseph C.
Robbins Paul D.
Sim & Mcburney
University Of Pittsburgh Of The Commonwealth System Of Higher Ed
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