Gene transfer method

Details Gene transfer method Gene transfer method

C - Chemistry, Metallurgy

12

N

C12N 15/87 (2006.01) A61K 48/00 (2006.01) A61N 7/00 (2006.01)

Patent

CA 2609817

An efficient method of transferring a gene to a target cell is provided. The method of transferring a gene to a target cell is characterized by adding or administering (A) a positively charged complex composed of the gene and a cationic substance and (B) a gas-containing small particle to a composition or living body containing the target cell and irradiating with a low-frequency ultrasonic wave.

L~invention concerne un procédé efficace de transfert d~un gène vers une cellule cible. Ce procédé de transfert d~un gène vers une cellule cible se caractérise par l~ajout ou l~administration (A) d~un complexe positivement chargé, composé du gène et d~une substance cationique, et (B) d~une petite particule contenant un gaz dans une composition ou un organisme vivant contenant la cellule cible, et par l~irradiation avec un ultrason basse fréquence.

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