C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2620082
The present invention relates to the selection of a set of polymorphism markers for use in genome wide association studies based on linkage disequilibrium mapping. In particular, the invention relates to the fields of pharmacogenomics, diagnostics, patient therapy and the use of genetic haplotype information to predict an individual's susceptibility to Crohn's disease and/or their response to a particular drug or drugs.
L'invention concerne la sélection d'un ensemble de marqueurs de polymorphismes destinés à être utilisés dans des études de large association avec le génome en fonction de la cartographie du déséquilibre de liaison. Plus spécifiquement, cette invention concerne les champs de la pharmacogénomique, du diagnostic, de la thérapie du patient ainsi que l'utilisation d'informations d'haplotype génétique pour prévoir une susceptibilité individuelle à la maladie de Crohn et/ou la réponse individuelle à un médicament particulier ou à des médicaments particuliers.
Allard Rene
Belouchi Abdelmajid
Bradley Walter Edward
Croteau Pascal
Debrus Sophie
Genizon Biosciences Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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