C - Chemistry – Metallurgy – 40 – B
Patent
C - Chemistry, Metallurgy
40
B
C40B 40/06 (2006.01) A61K 31/00 (2006.01) A61K 31/7088 (2006.01) A61K 38/00 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) C12Q 1/68 (2006.01) C40B 30/04 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2679091
The present invention relates to the selection of a set of polymorphism markers for use in genome wide association studies based on linkage disequilibrium mapping. In particular, the invention relates to the fields of pharmacogenomics, diagnostics, patient therapy and the use of genetic haplotype information to predict an individual's susceptibility to SCHIZOPHRENIA disease and/or their response to a particular drug or drugs.
Cette invention concerne la sélection d'un ensemble de marqueurs de polymorphisme utilisables dans les études d'association sur le génome entier reposant sur la cartographie des déséquilibres de liaison. En particulier, l'invention concerne les domaines de la pharmacogénomique, du diagnostic, du traitement thérapeutique, et l'utilisation des données concernant les haplotypes génétiques pour prédire la sensibilité d'un sujet à la schizophrénie et/ou sa réponse à un/des médicament(s) donné(s).
Belouchi Abdelmajid
Bradley Walter Edward
Bruat Vanessa
Croteau Pascal
Dubois Daniel
Genizon Biosciences Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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