Generation of a cancer-specific immune response toward muc1...

A - Human Necessities – 61 – K

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A61K 39/00 (2006.01) A61K 49/00 (2006.01) A61P 35/00 (2006.01) C07K 14/705 (2006.01) C07K 16/30 (2006.01) C12N 5/16 (2006.01) C12P 21/08 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2665356

The present invention provides a method for inducing a cancer specific immune response against MUC1 using an immunogenic glycopeptide. Other aspects of the invention are a pharmaceutical composition comprising the immunogenic glycopeptide and a cancer vaccine comprising the immunogenic glycopeptide. Another aspect is an antibody generated using the immunogenic glycopeptide and the use of said antibody in therapy and diagnosis.

La présente invention concerne un procédé permettant d'induire une réponse immune spécifique du cancer contre MUC1 grâce à un glycopeptide immunogène. D'autres aspects de l'invention portent sur une composition pharmaceutique contenant le glycopeptide immunogène et sur un vaccin anticancéreux contenant le glycopeptide immunogène. Un autre aspect encore porte sur un anticorps généré grâce au glycopeptide immunogène et sur l'utilisation dudit anticorps à des fins thérapeutiques et diagnostiques.

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