Generation of angiotensin i from angiotensinogen by...

Details Generation of angiotensin i from angiotensinogen by... Generation of angiotensin i from angiotensinogen by...

G - Physics

01

N

167/40

G01N 33/00 (2006.01) G01N 33/539 (2006.01) G21H 5/02 (2006.01)

Patent

CA 1095405

Abstract In a radioimmunoassay for the determination of plasma renin activity, the use of a buffer solution of pH about 7.4 in the incubation of plasma samples, said buffer comprising about equimolar amounts of tris (hydroxymethyl) aminomethane and maleic acid, results in a high generation of angiotensin I. This process results in an improved test- ing prodcedure compared with the known art and it is useful in a radioimmunoassay for the determination of angiotensin I in a plasma sample.

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