Generation of fully mature and stable dendritic cells from...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/0784 (2010.01) C12N 5/078 (2010.01) A61K 35/14 (2006.01) C12M 3/00 (2006.01) C12M 3/04 (2006.01) A61K 35/12 (2006.01) C12M 1/14 (2006.01) C12M 1/20 (2006.01) C12M 1/24 (2006.01)

Patent

CA 2455327

The present invention provides a method for producing mature and stable dendritic cells or immature dendritic cells which comprises cultivating hematopoietic progenitor cells in a sterile cultivating apparatus, an apparatus suitable for said method and a method for preparing peripheral blood mononuclear cells, which are suitable for cultivation of dendritic cells.

L'invention concerne une méthode qui permet de produire des cellules dendritiques stables et arrivées à pleine maturité ou des cellules dendritiques immatures, cette méthode consistant à cultiver des cellules souches hématopoïétiques dans un appareil de culture stérile. L'invention concerne également un appareil destiné à mettre en oeuvre cette méthode ainsi qu'une méthode de préparation de cellules sanguines mononucléaires périphériques, qui conviennent pour la culture de cellules dendritiques.

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