Generation of inner ear cells

Details Generation of inner ear cells Generation of inner ear cells

C - Chemistry, Metallurgy

12

N

C12N 5/0797 (2010.01) C12N 5/0775 (2010.01) A61K 35/12 (2006.01) A61K 35/30 (2006.01)

Patent

CA 2669693

Methods for generating cells of the inner ear, e.g., hair cells and supporting cells, from stem cells, e.g., mesenchymal stem cells, are provided, as well as compositions including the inner ear cells. Methods for the therapeutic use of the inner ear cells for the treatment of hearing loss are also described.

L'invention concerne un procédé pour générer des cellules de l'oreille interne, par exemple des cellules auditives et des cellules de support, à partir de cellules souches, par exemple de cellules souches mésenchymateuses, ainsi que des compositions comprenant les cellules de l'oreille interne. Des procédés d'utilisation thérapeutique des cellules de l'oreille interne pour le traitement de la perte auditive sont également décrits.

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