C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/52 (2006.01) C07K 16/46 (2006.01) C12N 1/21 (2006.01) C12N 15/57 (2006.01) C12N 15/62 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01)
Patent
CA 2553807
The present invention refers to an expression vector for gram-negative bacteria allowing for the production of hybrid proteins between single domain recombinant antibodies and a transporter domain of an autotransporter, as well as to its anchoring and expression on the external surface of a bacterial membrane, and to a method of specific bacterial adhesion to a surface containing a specific antigen.
L'invention concerne un vecteur d'expression pour des bactéries Gram négatif permettant de produire des protéines hybrides entre des anticorps recombinés à domaine unique et un domaine de transport d'un autotransporteur, ainsi que sa fixation et que son expression sur la surface extérieure d'une membrane bactérienne, et un procédé d'adhérence bactérienne spécifique à une surface contenant un antigène spécifique.
de Lorenzo Prieto Victor
Fernandez Herrero Luis Angel
Veiga Chacon Esteban
Consejo Superior de Investigaciones Cientificas
Rogers Law Office
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