Generator and method for production of technetium-99m

C - Chemistry – Metallurgy – 01 – G

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C01G 99/00 (2010.01) G21G 4/04 (2006.01)

Patent

CA 2583568

A generator that allows for a non-fission based method of producing and recovering 99mTcfrom neutron-irradiated molybdenum. This generator system is based on the isolation of 99mTc, as the decay product from a source of 99Mo labelled molybdenum carbonyl Mo(CO)6 through a distillation process. The 99mTcobtained from this distillation is produced with high efficiency and purity in a solvent-free form, which can then be dissolved in water or other solvents to produce a solution at the required specific activity and concentration, as reasonably determined by the operator.

L'invention concerne un générateur qui permet d'appliquer un procédé sans fission d'obtention et de récupération de 99mTc à partir de molybdène irradié par les neutrons. Le système de générateur repose sur l'isolation de 99mTc, comme produit de désintégration d'une source de 99Mo appelé molybdène carbonyle Mo(CO)6, au moyen d'un procédé de distillation. Le 99mTcrésultant de cette distillation est produit avec un grand rendement et une pureté élevée sous une forme exempte de solvant, laquelle peut être ensuite dissoute dans l'eau ou dans d'autres solvants pour obtenir une solution qui répond aux exigences raisonnablement déterminées par l'opérateur, en terme d'activité spécifique et de concentration.

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