C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07H 21/00 (2006.01) C07K 7/04 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2184580
The invention provides genetic suppressor elements that confer the transformed phenotype of malignant mammalian cells upon untransformed cells, methods for identifying and obtaining such elements, methods for isolating and identifying genes corresponding to such elements, and methods of using such elements. The invention also provides genes corresponding to the GSEs of the invention.
L'invention concerne des éléments génétiques suppressifs qui confèrent le phénotype transformé de cellules de mammifère malignes sur des cellules non transformées. L'invention concerne également des méthodes pour identifier et obtenir de tels éléments, des méthodes pour isoler et identifier les gènes correspondant à de tels éléments, et des méthodes d'utilisation de ces éléments. On décrit également des gènes correspondant aux éléments génétiques suppressifs de l'invention.
Gudkov Andrei
Kazarov Alexander
Mazo Ilya
Roninson Igor B.
Mbm & Co.
The Board Of Trustees Of The University Of Illinois
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