Genes associated with colorectal cancer

Details Genes associated with colorectal cancer Genes associated with colorectal cancer

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2587863

We describe a method for the identification of genes which show regulated expression in response to carbon source utilisation, typically genes associated with the initiation and/or promotion of cell transformation from a non-cancerous to a cancerous phenotype, typically of cells found in the colon; the use of these genes in diagnostic assays and as targets for the development of chemotherapeutic drugs and agents identified by said assay.

L'invention a pour objet un procédé d'identification de gènes faisant preuve d'une expression régulée en réponse à l'utilisation d'une source carbone, notamment des gènes en rapport avec des opérations de lancement et/ou favorisant la transformation cellulaire à partir d'un phénotype cancéreux vers un phénotype cancéreux, normalement des cellules se trouvant dans le colon; l'utilisation de ces gènes dans des essais diagnostiques et comme cibles pour la mise au point de médicaments chimiothérapeutiques et des agents identifiés par ledit essai.

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