Genes encoding g-protein coupled receptors and methods of...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A01K 67/00 (2006.01) A61K 35/12 (2006.01) A61K 38/16 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) C07H 21/02 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 15/62 (2006.01) C12N 15/63 (2006.01) C12N 15/90 (2006.01) C12Q 1/00 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2467206

The present invention relates generally to the fields of neuroscience, bioinformatics and molecular biology. More particularly, the invention relates to newly identified polynucleotides that encode G-protein coupled receptors (GPCRs), the use of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides. The invention relates also to identifying compounds which may be agonists, antagonists and/or inhibitors of GPCRs, and therefore potentially useful in therapy.

L'invention concerne d'une manière générale les domaines de la neuroscience, de la bioinformatique et de la biologie moléculaire. Plus précisément, l'invention concerne des polynucléotides nouvellement identifiés qui codent pour des récepteurs couplés à la protéine G (GPCR), l'utilisation de ces polynucléotides et polypeptides, ainsi que leur production. L'invention concerne enfin l'identification de composés qui peuvent être des agonistes, des antagonistes et/ou des inhibiteurs de GPCR, donc potentiellement utiles en thérapie.

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