Genes encoding the human fk-506 binding protein and a.s....

Details Genes encoding the human fk-506 binding protein and a.s.... Genes encoding the human fk-506 binding protein and a.s....

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 14/47 (2006.01) C12N 1/21 (2006.01) C12N 9/90 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2052928

9944P 18243 TITLE OF THE INVENTION GENES ENCODING THE HUMAN FK-506 BINDING PROTEIN AND a S. CEREVISIAE HOMOLOG, FKB1, AND THEIR EXPRESSION ABSTRACT OF THE DISCLOSURE The genes encoding the human FK-506 binding protein and a S. cerevisiae homolog, FKB1, are described, as well as their expression and the amino acid sequences of the protein products. These binding proteins are useful, inter alia, for screening compounds useful as immunosuppressive drugs that block allograft rejection by preventing T-cell activation.

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