Genes encoding the synthetic pathway for the production of...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/52 (2006.01) C12N 1/21 (2006.01) C12N 9/00 (2006.01) C12N 15/31 (2006.01) C12P 17/18 (2006.01)

Patent

CA 2594790

The present invention relates to nucleic acid sequences and proteins derivable therefrom that have been identified in Sorangium cellulosum, which proteins are catalytically active or participate in the biosynthetic pathway of disorazoles. The invention provides novel sequences which are necessary components of the disorazole biosynthetic pathway in addition to genes dszA-D.

L'invention porte sur des séquences nucléotidiques et des protéines pouvant être dérivées de ces dernières, et identifiées dans Sorangium cellulosum, lesdites protéines ayant une activité catalytique ou participant à la voie de synthèse biologique des disorazoles. L'invention a trait à de nouvelles séquences qui sont des composants nécessaires de la voie de synthèse biologique des disorazoles en plus des gènes dszA-D.

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