C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/52 (2006.01) C07K 14/27 (2006.01) C12N 9/00 (2006.01) C12N 15/31 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2190835
DNA involved in the bacterial gene expression of carbapenem antibiotics comprising: a) at least one of the genes carA,carB,carC,carD,carE,carF,carG,carH, b) DNA capable of hybridising to any of the genes defined in a) and capable of functioning as such genes in the biosynthetic pathway of a carbapenem, c) DNA which is equivalent to DNA defined in either a) or b) above by virtue of the degeneracy of the genetic code. Polypeptides encoded by such DNA.
De l'ADN impliqué dans l'expression de gènes bactériens d'antibiotiques à base d'un carbapénem comprend: a) au moins un des gènes <u>carA</u>,<u>carB</u>,<u>carC</u>,<u>carD</u>,<u>carE</u>,<u>carF</u>,<u>carG</u>,<u>carH</u>, b) de l'ADN pouvant s'hybrider à l'un quelconque des gènes définis en a) et pouvant fonctionner comme de tels gènes dans la voie biosynthétique d'un carbapénem, et c) de l'ADN équivalent à l'ADN défini en a) ou b) en vertu de la dégénérescence du code génétique. On décrit des polypeptides codés par de tels ADN.
Bycroft Barrie Walsham
Cox Anthony Richard John
Holden Matthew Thomas Geoffrey
Mcgowan Simon James
Porter Lauren Elizabeth
Sim & Mcburney
The University Of Nottingham
University Of Warwick
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