Genes of an otitis media isolate of nontypeable haemophilus...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/31 (2006.01) A61K 39/102 (2006.01) A61P 31/04 (2006.01) C07K 14/285 (2006.01) C07K 16/12 (2006.01)

Patent

CA 2612240

The invention relates to the polynucleotide sequence of a nontypeable stain of Haemophilus influenzae (NTHi) and polypeptides encoded by the polynucleotides and uses thereof. The invention also relates to NTHi genes which are upregulated during or in response to NTHi infection of the middle ear and/or the nasopharynx.

Séquence polynucléotidique de souche non typable Haemophilus influenzae (NTHi) et polypeptides codés par les polynucléotides, et utilisations. Egalement gènes NTHi à régulation positive durant l'infection NTHi ou en réaction à celle-ci, s'agissant de l'oreille moyenne et/ou du nasopharynx.

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