Genes overexpressed in prostate disorders as diagnostic and...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/86 (2006.01) A61K 31/7088 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C12N 15/63 (2006.01) C12N 15/861 (2006.01) C12Q 1/68 (2006.01) C40B 30/00 (2006.01) C40B 30/04 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2432991

Disclosed are methods for diagnosing, monitoring the progression of, and treating a prostate disorder based upon genes that are differentially expressed in prostate disorders. Also disclosed are methods for identifying agents useful in the treatment of a prostate disorder, methods for monitoring the efficacy of a treatment for a prostate disorder, methods for inhibiting the proliferation of a prostate cell, and prostate-specific vectors including the promoter of these genes.

L'invention concerne des procédés de diagnostic, de contrôle de la progression, et de traitement d'une maladie de la prostate sur la base de gènes exprimés de manière différentielle dans des maladies de la prostate. L'invention concerne également des procédés d'identification d'agents servant au traitement de maladies de la prostate, des procédés d'inhibition de la prolifération d'une cellule prostatique, et des vecteurs spécifiques à la prostate, y compris les promoteurs de ces gènes.

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