C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A01K 67/027 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/00 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2344978
The invention concerns genes, polymorphisms and polypeptides related to central nervous systems disease. Included are the G713 gene, the G713 protein and G713 biallelic markers, as well as biallelic markers located on the human chromosome 13q31-q33 locus, and the association established between these biallelic markers and schizophrenia. The invention also provides means to determine the predisposition of individuals to schizophrenia as well as means for the diagnosis of this disease and for the prognosis and detection of an eventual treatment response to therapeutic agents acting against schizophrenia.
L'invention concerne des gènes, des polymorphismes et des polypeptides liés à une maladie du système nerveux central, en particulier le gène G713, la protéine G713 et les marqueurs bialléliques G713. L'invention concerne également les marqueurs bialléliques se trouvant sur le chromosome humain 13q31-q33 locus, et la relation établie entre ces marqueurs et la schizophrénie. L'invention concerne également des moyens permettant de déterminer la prédisposition d'individus à la schizophrénie ainsi que des moyens permettant de diagnostiquer cette maladie, de pronostiquer et de détecter l'éventuelle réponse d'un traitement à des agents thérapeutiques agissant contre la schizophrénie.
Blumenfeld Marta
Bougueleret Lydie
Chumakov Ilya
Cohen Daniel
Essioux Laurent
Genset
Sim & Mcburney
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