Genetic adjuvants for viral vaccines

A - Human Necessities – 61 – K

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Details

A61K 39/00 (2006.01) A61K 39/21 (2006.01) A61P 31/18 (2006.01) A61P 37/04 (2006.01) C12N 15/86 (2006.01) C12N 15/864 (2006.01)

Patent

CA 2650375

The present invention relates to compositions and methods to improve expression of exogenous polypeptides, such as an antigen, epitope, immunogen, peptide or polypeptide of interest, in viral vaccines. More particularly, the present invention provides for viral vaccines with increased adjuvantation via a genetic adjuvant.

La présente invention concerne des compositions et des procédés destinés à améliorer l'expression de polypeptides exogènes, tels qu'un antigène, un épitope, un immunogène, un peptide ou un polypeptide d'intérêt, dans des vaccins viraux. Plus particulièrement, la présente invention concerne des vaccins viraux dont l'adjuvantation est accrue au moyen d'un adjuvant génétique.

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