Genetic and protein therapy products for treating cystic...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 38/45 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C12N 9/10 (2006.01) C12N 15/54 (2006.01) C12N 15/86 (2006.01) C12N 15/88 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2298062

The invention concerns a DNA molecule containing a DNA sequence whereof the expression product has a common peptide sequence with part of that of CFTR, in particular the one extending from the 430<th> to the 660<th> residue of the latter and having a glutathione carrier function. Said DNA molecule is useful for constructing vectors useful in gene therapy for treating cystic fibrosis.

The invention concerns a DNA molecule containing a DNA sequence whereof the expression product has a common peptide sequence with part of that of CFTR, in particular the one extending from the 430 th to the 660 th residue of the latter and having a glutathione carrier function. Said DNA molecule is useful for constructing vectors useful in gene therapy for treating cystic fibrosis.

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