Genetic markers for risk management of atrial fibrillation...

Details Genetic markers for risk management of atrial fibrillation... Genetic markers for risk management of atrial fibrillation...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2757384

The invention relates to procedures and methods of determining a susceptibility to cardiac arrhythmia, including Atrial Fibrillation, Atrial Flutter and Stroke, by assessing the presence or absence of alleles at polymorphic markers found to be associated with risk of these conditions. The invention further relates to kits encompassing reagents for assessing such markers, and diagnostic 5 methods, uses and procedures for utilizing such susceptibility markers.

L'invention porte sur des procédures et des procédés de détermination d'une prédisposition à une arythmie cardiaque, comprenant une fibrillation auriculaire, un flutter auriculaire, et un accident vasculaire cérébral, par évaluation de la présence ou de l'absence d'allèles au niveau de marqueurs polymorphes trouvés être associés à un risque de ces états. L'invention porte en outre sur des coffrets englobant des réactifs pour évaluer de tels marqueurs, et sur des procédés de diagnostic, des utilisations et des procédures pour utiliser de tels marqueurs de prédisposition.

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