Genetic markers for risk management of cardiac arrhythmia

Details Genetic markers for risk management of cardiac arrhythmia Genetic markers for risk management of cardiac arrhythmia

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2673123

The invention relates to procedure and methods of determining a susceptibility to cardiac arrhythmia, including Atrial Fibrillation, Atrial Flutter and Stroke, by assessing the presence or absence of alleles at polymorphic markers found to be associated with Atrial Fibrillation, Atrial Flutter and Stroke. The invention further relates to kits encompassing reagents for assessing such markers, and diagnostic methods, uses and procedures for utilizing such susceptibility markers.

L'invention porte sur une procédure et des procédés destinés à déterminer une sensibilité à l'arythmie cardiaque, comprenant une fibrillation auriculaire, un flutter auriculaire et un accident cérébrovasculaire, par l'évaluation de la présence ou de l'absence d'allèles au niveau de marqueurs polymorphes reconnus être associés à une fibrillation auriculaire, un flutter auriculaire et un accident cérébrovasculaire. L'invention concerne en outre des kits contenant des réactifs pour évaluer de tels marqueurs, et des procédés de diagnostic, des utilisations et des procédures servant à utiliser de tels marqueurs de sensibilité.

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