Genetic markers for weight management and methods of use...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01) G06F 19/00 (2011.01)

Patent

CA 2724497

This application relates to methods and tests that allow for the establishment of personalized weight-loss programs for a subject based upon the subject's metabolic genotype in key metabolic genes. Kits and methods are disclosed for determining a subject's metabolic genotype, which may be used to select an appropriate therapeutic/dietary regimen or lifestyle recommenda-tion based upon the likelihood of a subject's responsiveness to certain diets and activity levels. Such a personalized weight-loss program will have obvious benefits (e.g., yield better results in terms of weight loss and weight maintenance) over traditional weight-loss programs that do not take into account genetic information.

L'invention concerne des procédés et des examens qui permettent d'établir des programmes d'amaigrissement personnalisés pour un sujet, et qui s'appuient sur le génotype métabolique de ce dernier pour mettre en lumière ses gènes métaboliques clés. Des kits et des procédés de l'invention permettent de déterminer le génotype métabolique du sujet, lequel peut servir à choisir le schéma thérapeutique/diététique ou les recommandations en termes de mode de vie appropriés, sur la base de la probabilité selon laquelle le sujet sera réceptif à certains régimes et à certains niveaux d'activité. Un tel programme d'amaigrissement personnalisé présente d'indéniables avantages (notamment, l'obtention de meilleurs résultats en termes d'amaigrissement et de stabilisation du poids) en comparaison avec les programmes d'amaigrissement classiques qui ne prennent pas en compte les données génétiques.

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