C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2566256
The present invention is based on the discovery of genetic polymorphisms that are associated with liver fibrosis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
La présente invention concerne la découverte que des polymorphismes génétiques sont associés à la cirrhose du foie et à des pathologies associées. Cette invention concerne en particulier des molécules d'acides nucléiques contenant ces polymorphismes, des protéines de variant codées par ces molécules d'acides nucléiques, des réactifs permettant de détecter ces molécules et ces protéines d'acides nucléiques polymorphiques et, des techniques d'utilisation de ces acides nucléiques et de ces protéines ainsi que des techniques d'utilisation de réactifs permettant leur détection.
Cargill Michele
Huang Hongjin
Applera Corporation
Celera Corporation
Fetherstonhaugh & Co.
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