C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07H 21/04 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01)
Patent
CA 2518957
The present invention is based on the discovery of genetic polymorphisms that are associated with myocardial infarction. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
L'invention concerne la découverte des polymorphismes génétiques associés à l'infarctus du myocarde. En particulier, l'invention concerne les molécules d'acides nucléiques comportant les polymorphismes, les protéines hybrides codées par lesdites molécules d'acides nucléiques, les réactifs pour la détection des molécules polymorphiques d'acides nucléiques et des protéines ainsi que des procédés d'utilisation dudit acide nucléique et desdites protéines et des procédés d'utilisation de réactifs pour leur détection.
Cargill Michele
Devlin James J.
Iakoubova Olga
Shiffman Dov
Applera Corporation
Celera Corporation
Fetherstonhaugh & Co.
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