C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07H 21/00 (2006.01) C07H 21/04 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2511012
The present invention is based on the discovery of genetic polymorphisms that are associated with myocardial infarction. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
On a découvert que des polymorphismes génétiques sont associés à l'infarctus du myocarde. La présente invention concerne en particulier des molécules d'acides nucléiques contenant ces polymorphismes, des protéines de variant codées par ces molécules d'acides nucléiques, des réactifs permettant de détecter ces protéines et ces molécules d'acides nucléiques polymorphiques et, des techniques d'utilisation de ces acides nucléiques et de ces protéines, ainsi que des techniques d'utilisation de réactifs destinés à leur détection.
Cargill Michele
Devlin James J.
Iakoubova Olga
Applera Corporation
Celera Corporation
Fetherstonhaugh & Co.
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