C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2514950
The present invention is based on the discovery of genetic polymorphisms that are associated with rheumatoid arthritis. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
L'invention concerne la découverte de polymorphismes génétiques qui sont associés à l'arthrite rhumatoïde. Plus particulièrement, cette invention concerne des molécules d'acide nucléique contenant les polymorphismes, des variants de protéines codés par ces molécules d'acide nucléique, des réactifs permettant de détecter les molécules et les protéines d'acide nucléique polymorphe. L'invention concerne aussi des procédés d'utilisation d'acide nucléique et de protéines ainsi que des procédés d'utilisation de réactifs pour les détecter.
Alexander Heather Camille
Begovich Ann Bethea
Cargill Michelle
Carlton Victoria Elizabeth
Schrodi Steven Jon
Applera Corporation
Celera Corporation
Fetherstonhaugh & Co.
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