C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2519476
The present invention is based on the discovery of genetic polymorphisms that are associated with rheumatoid arthritis. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
L'invention concerne la découverte de polymorphismes génétiques associés à la polyarthrite rhumatoïde. Elle concerne, en particulier, des molécules d'acide nucléique contenant ces polymorphismes, des protéines variantes codées par ces molécules d'acide nucléique, des réactifs servant à détecter ces protéines et ces molécules d'acide nucléique polymorphes, ainsi que des méthodes d'utilisation de ces acides nucléiques et de ces protéines et des méthodes d'utilisation de réactifs afin de détecter ces acides nucléiques et ces protéines.
Alexander Heather C.
Begovich Ann B.
Cargill Michele
Applera Corporation
Celera Corporation
Fetherstonhaugh & Co.
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