C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2555259
The present invention is based on the discovery of genetic polymorphisms that are associated with vascular diseases, particularly stroke. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
La présente invention repose sur la découverte de polymorphismes génétiques qui sont associés à des maladies vasculaires, en particulier à l'accident vasculaire cérébral. Cette invention concerne en particulier des molécules d'acide nucléique contenant ces polymorphismes, des protéines variantes codées par ces molécules d'acide nucléique, des réactifs permettant de détecter les molécules d'acide nucléique et protéines polymorphiques, des méthodes d'utilisation de l'acide nucléique et des protéines ainsi que des méthodes d'utilisation de ces réactifs pour la détection.
Cargill Michele
Devlin James
Luke May
Applera Corporation
Celera Corporation
Fetherstonhaugh & Co.
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