C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07H 21/00 (2006.01) G01N 33/53 (2006.01) A61K 39/395 (2006.01)
Patent
CA 2666346
The present invention is based on the discovery of genetic polymorphisms that are associated with coronary heart disease and in particular VT and response to drug treatment. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
La présente invention est fondée sur la découverte de polymorphismes génétiques associés à la maladie coronarienne, en particulier la thrombose veineuse, ainsi que sur la réponse au traitement médicamenteux. L'invention concerne en particulier des molécules d'acide nucléique contenant lesdits polymorphismes, des variantes de protéines codées par lesdites molécules d'acide nucléique, des réactifs destinés à détecter les molécules d'acides nucléiques polymorphes et les protéines, ainsi que des procédés utilisant l'acide nucléique et les protéines et des procédés utilisant des réactifs pour les détecter.
Bare Lance
Celera Corporation
Fetherstonhaugh & Co.
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