C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/00 (2006.01) C07K 14/28 (2006.01) C07K 16/44 (2006.01) C12N 1/20 (2006.01) C12Q 1/02 (2006.01)
Patent
CA 2125536
Abstract of the disclosure Genetic selection, by means of signal transduction in microorganisms, of proteins which are capable of ligand binding The invention relates to a process for the genetic selection in microorganisms of proteins which are capable of ligand binding, in which process a protein which is capable of ligand binding is presented extra- cytoplasmically and the signal of the ligand binding is passed on by signal transduction to the biosynthetic machinery of the microorganism for the purpose of ex- pressing a detectable and/or selectable function. In addition to this, the patent discloses microorganisms which are suitable for use in this process, as well as replicons and processes for their preparation.
Fritz Hans-Joachim
Hennecke Frank
Kolmar Harald
Behringwerke Aktiengesellschaft
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
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