Genetic susceptibility variants of type 2 diabetes mellitus

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01)

Patent

CA 2683909

Association analysis has shown that certain genetic variants are susceptibility variants for Type 2 diabetes. The invention relates to diagnostic applications of such susceptibility variants, including methods of determining increased susceptibility to Type 2 diabetes, as well as methods of determining decreased susceptibility to Type 2 diabetes in an individual. The invention further relates to kits for determining a susceptibility to Type 2 diabetes based on the variants described herein.

L'analyse par association a démontré que certaines variantes génétiques sont des variantes de susceptibilité au diabète mellitus de type 2. L'invention porte sur des applications diagnostiques desdites variantes de susceptibilité, notamment des procédés permettant de déterminer une susceptibilité augmentéee au diabète de type 2 et des procédés permettant de déterminer une susceptibilité réduite au diabète de type 2 chez un individu. L'invention concerne en outre des trousses qui permettent de déterminer une susceptibilité au diabète de type 2 sur la base des variantes de l'invention.

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