Genetic variants for breast cancer risk assessment

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01)

Patent

CA 2729934

The invention pertains to certain genetic variants that have been determined to be susceptibility variants of breast cancer. Methods of disease management, including diagnosing increased susceptibility to breast cancer, methods of predicting response to therapy and methods of predicting prognosis using such variants are described. The invention further relates to kits useful in the methods of the invention.

L'invention porte sur certaines variantes génétiques s'étant avérées être des variantes de prédisposition au cancer du sein. L'invention porte également sur des méthodes de gestion de maladies incluant le diagnostic d'une prédisposition accrue au cancer du sein, sur des méthodes de prédiction de la réponse à une thérapie, et sur des méthodes d'établissement de pronostics à l'aide desdites variantes. L'invention porte en outre sur des trousses utilisables avec les méthodes selon l'invention.

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