Genetic variants useful for risk assessment of thyroid cancer

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2733910

The invention discloses genetic variants that have been determined to be susceptibility variants of thyroid cancer. Methods of disease management, including determining increased susceptibility to thyroid cancer, methods of predicting response to therapy and methods of predicting prognosis of thyroid cancer using such variants are described. The invention further relates to kits useful in the methods of the invention.

L'invention porte sur des variants génétiques qui ont été déterminés comme étant des variants de susceptibilité du cancer de la thyroïde. L'invention porte sur des procédés de gestion de maladie, comprenant la détermination d'une susceptibilité accrue au cancer de la thyroïde, sur des procédés de prédiction d'une réponse à une thérapie et sur des procédés de prédiction d'un pronostic du cancer de la thyroïde à l'aide de tels variants. L'invention porte en outre sur des kits utiles dans les procédés de l'invention.

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