Genetically engineered biological indicator

Details Genetically engineered biological indicator Genetically engineered biological indicator

C - Chemistry, Metallurgy

12

Q

C12Q 1/22 (2006.01) A61L 2/00 (2006.01) A61L 2/26 (2006.01) C12Q 1/04 (2006.01) C12Q 1/25 (2006.01) C12Q 1/68 (2006.01) C12N 15/65 (2006.01)

Patent

CA 2667698

The disclosed technology relates to a genetically engineered biological indicator, comprising: at least one test organism and at least one reporter gene suitable for producing an indicator enzyme, the reporter gene being taken up by the test organism; and at least one repressor gene that inhibits expression of the reporter gene until the reporter gene is exposed to at least one inducer. A process and an apparatus for using the biological indicator are disclosed.

La présente invention concerne une technologie relative à un indicateur biologique génétiquement modifié qui comprend : au moins un organisme cobaye et au moins un gène rapporteur approprié pour produire une enzyme d'indication, le gène rapporteur étant absorbé par l'organisme cobaye; et au moins un gène répresseur qui inhibe l'expression du gène rapporteur jusqu'à l'exposition du gène rapporteur à au moins un inducteur. Un procédé et un appareil d'utilisation de l'indicateur biologique sont décrits.

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