Genetically engineered human-derived kunitz domains that...

Details Genetically engineered human-derived kunitz domains that... Genetically engineered human-derived kunitz domains that...

C - Chemistry, Metallurgy

12

N

C12N 15/15 (2006.01) A61K 38/57 (2006.01) C07K 14/81 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2207820

This invention relates to novel proteins that inhibit human neutrophil elastase (hNE). A large fraction of the sequence of each of these proteins is identical to a known human protein which has very little or no inhibitory activity with respect to hNE.

L'invention concerne de nouvelles protéines inhibant l'élastase des neutrophiles chez l'homme (hNE). Une fraction importante de la séquence de chacune de ces protéines est identique à une protéine connue de l'homme, qui présente une activité d'inhibition extrêmement limitée ou nulle par rapport à hNE.

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