Genetically modified cells and methods for expressing...

Details Genetically modified cells and methods for expressing... Genetically modified cells and methods for expressing...

C - Chemistry, Metallurgy

12

N

C12N 1/21 (2006.01) C12N 1/15 (2006.01) C12N 1/19 (2006.01) C12N 5/10 (2006.01) C12N 9/24 (2006.01) C12N 15/09 (2006.01) C12N 15/56 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2329142

Bacterial, yeast and animal cells and methods for overexpressing recombinant heparanase in cellular systems, methods of purifying recombinant heparanase therefrom and modified heparanase species which serve as precursors for generating highly active heparanase by proteolysis.

Cellules de bactéries, de levures et d'animaux et procédés servant à surexprimer héparanase de recombinaison dans des systèmes cellulaires ; procédés servant à purifier héparanase de recombinaison exprimée par lesdits systèmes et espèces modifiées d'héparanase servant de précurseurs afin de générer par protéolyse héparanase extrêmement active.

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