Genetically modified human hematopoietic stem cells and...

Details Genetically modified human hematopoietic stem cells and... Genetically modified human hematopoietic stem cells and...

C - Chemistry, Metallurgy

12

N

C12N 5/10 (2006.01) A61K 35/18 (2006.01) A61K 35/28 (2006.01) A61K 48/00 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2170980

Human hematopoietic stem cells expressing recombinant DNA constructs encoding a recombinant molecule containing a signal transducing region and an antigenic specificity region results in the generation of T cells with altered specificities.

Des cellules souches hématopoiëtiques humaines expriment un ADN, qui est un produit d'assemblage obtenu par recombinaison et qui est capable de coder une molécule de recombinaison contenant une région de transduction de signaux et une région de spécificité antigénique, et permettent de produire des lymphocytes T avec des spécificités modifiées.

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