Genetically treated animals

A - Human Necessities – 61 – K

Patent

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Details

A61K 48/00 (2006.01) A01K 67/027 (2006.01) A61K 31/70 (2006.01) A61K 35/12 (2006.01) C12N 5/10 (2006.01) C12N 9/52 (2006.01) C12N 15/85 (2006.01) C12N 15/86 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2220472

The present invention relates to DNA sequences, expression cassettes and DNA constructs for use in therapy, specifically in gene therapy for the treatment of infectious diseases such as mastitis. Also included are pharmaceutical and veterinary compositions containing the constructs, and cells which have been transformed with the DNA and which are suitable for implantation into a host mammal. The gene therapy of infectious diseases can be effected in situ in targeted tissue or systemically.

La présente invention concerne des séquences d'ADN, des cassettes d'expression et des produits de synthèse d'ADN à usage thérapeutique, notamment pour la thérapie génique de maladies infectieuses telles que la mammite. Elle concerne également des compositions pharmaceutiques et vétérinaires contenant ces produits de synthèse, ainsi que des cellules qui ont été transformées avec l'ADN et qui se prêtent à l'implantation chez un mammifère hôte. La thérapie génique de maladies infectieuses peut s'appliquer in situ à des tissus ciblés ou de manière systémique.

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