Genomic sequence of the purh gene and purh-related biallelic...

Details Genomic sequence of the purh gene and purh-related biallelic... Genomic sequence of the purh gene and purh-related biallelic...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07K 14/00 (2006.01) C12N 9/10 (2006.01) C12N 15/52 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2368672

The invention concerns the genomic sequence of the PURH gene. The invention also concerns biallelic markers of a PURH gene and the association established between these markers and cancer, particularly prostate cancer. The invention provides means to determine the predisposition of individuals to cancer as well as means for the diagnosis of cancer and for the prognosis/detection of an eventual treatment response to agents acting on cancer.

L'invention concerne la séquence génomique du gène purH. Elle concerne également des marqueurs bialléliques d'un gène purH et l'association établie entre ces marqueurs et le cancer, en particulier le cancer de la prostate. L'invention concerne en outre des moyens qui permettent de déterminer la prédisposition des individus au cancer, ainsi que des moyens de diagnostiquer le cancer, de pronostiquer et de détecter une éventuelle réponse d'un traitement à des agents agissant contre le cancer.

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