C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/67 (2006.01) A61K 48/00 (2006.01) C07K 14/56 (2006.01) C12N 5/10 (2006.01) C12N 15/21 (2006.01) C12N 15/85 (2006.01) C12N 15/90 (2006.01)
Patent
CA 2328459
An isolated nucleic acid molecule that hybridizes under stringent conditions, or shares at least 80 % sequence identity, with a defined genomic region upstream of the coding region of the IFNA2 gene, and a DNA construct containing that DNA molecule as a targeting sequence for homologous recombination.
L'invention concerne une molécule isolée d'acide nucléique capable de s'hybrider, dans des conditions précises, ou de présenter une identité de séquence d'au moins 80 % avec une région génomique définie en amont de la région codant du gène IFNA2. L'invention concerne également une structure d'ADN contenant cette molécule d'ADN comme séquence cible pour la recombinaison homologue.
Heartlein Michael W.
Selden Richard F.
Treco Douglas A.
Mbm Intellectual Property Law Llp
Transkaryotic Therapies Inc.
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