Genomic sequences upstream of the coding region of the g-csf...

Details Genomic sequences upstream of the coding region of the g-csf... Genomic sequences upstream of the coding region of the g-csf...

C - Chemistry, Metallurgy

12

N

C12N 15/67 (2006.01) A61K 48/00 (2006.01) C07K 14/535 (2006.01) C12N 5/10 (2006.01) C12N 15/27 (2006.01) C12N 15/85 (2006.01) C12N 15/90 (2006.01)

Patent

CA 2328476

An isolated nucleic acid molecule that hybridizes under stringent conditions, or shares at least 80 % sequence identity, with a defined genomic region upstream of the coding region of the G-CSF gene, and a DNA construct containing that DNA molecule as a targeting sequence for homologous recombination.

L'invention concerne une molécule isolée d'acide nucléique capable de s'hybrider, dans des conditions précises, ou de présenter une identité de séquence d'au moins 80 % avec une région génomique définie en amont de la région codant du gène G-CSF. L'invention concerne également une structure d'ADN contenant cette molécule d'ADN comme séquence cible pour la recombinaison homologue.

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