Gingerol and gingerdiol derivatives as hypocholesterolemic...

Details Gingerol and gingerdiol derivatives as hypocholesterolemic... Gingerol and gingerdiol derivatives as hypocholesterolemic...

C - Chemistry, Metallurgy

07

C

C07C 43/23 (2006.01) A61K 31/05 (2006.01) A61K 31/085 (2006.01) A61K 31/12 (2006.01) C07C 39/11 (2006.01) C07C 45/62 (2006.01) C07C 45/67 (2006.01) C07C 45/71 (2006.01) C07C 45/72 (2006.01) C07C 49/245 (2006.01) C07C 49/255 (2006.01)

Patent

CA 2069548

ABSTRACT OF THE DISCLOSURE The present invention relates to a method of lowering plasma cholesterol, inhibiting the progression of atherosclerosis and inhibiting the peroxidation of LDL lipid in a patient in need thereof comprising administering to said patient an effective amount of a compound of the formula Image wherein R1 is hydrogen or C1-C4 alkyl, R2 is a C1-C12 alkyl, Y is O or OH, and Z is a bond when Y is O, or is hydrogen when Y is OH, M01610

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