Gitr antibodies for the diagnosis of nsclc

Details Gitr antibodies for the diagnosis of nsclc Gitr antibodies for the diagnosis of nsclc

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2592330

The present invention provides methods and compositions for detecting, diagnosing, prognosing and monitoring the progress of cancers, e.g., NSCLC, of epithelial origin, e.g., lung, ovarian, breast, prostate and colon cancers and malignancies and kits for use in said methods. Further provided are methods for screening to identify agonists and antagonists of antigens associated with these cancers and malignancies.

L'invention porte sur des procédés et des compositions qui permettent de détecter, diagnostiquer, pronostiquer et surveiller l'évolution des cancers, par exemple le cancer du poumon non à petites cellules (CPNPC), d'origine épithéliale, par exemple les cancers du poumon, de l'ovaire, du sein, de la prostate et du côlon et les tumeurs malignes, et sur des trousses à utiliser selon les procédés précités. L'invention concerne aussi des procédés de criblage permettant d'identifier des agonistes et des antagonistes d'antigènes associés auxdits cancers et tumeurs malignes.

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