Glass support coated with synthetic polymer for bioprocess

G - Physics – 01 – N

Patent

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G01N 33/50 (2006.01) A61K 39/44 (2006.01) C12N 11/08 (2006.01) C12N 11/14 (2006.01) G01N 33/552 (2006.01) G01N 33/58 (2006.01) G01N 33/78 (2006.01)

Patent

CA 1146854

ABSTRACT OF THE DISCLOSURE A new and useful process is disclosed for manufactur- ing a device for use in a bioprocess, comprising: (a) providing solid support means insoluble in water or organic solvent solutions; (b) coating said solid support means with organic- solvent based synthetic polymeric film means capable of apply- ing one or more biomaterials; and (c) adsorbing or covalently bonding at least one functional biomaterial to said polymeric film means. The polymeric film means, for example, can be used to coat antigens, antibodies, haptene, enzymes, living bac- teria, yeasts, etc. (i.e., biomaterials) to a glass (or other) support material, e.g., a glass tube, with surprising retention of the biomaterial's essential characteristic properties. The solid support means include but are not limited to those com- prising glass, ceramics, metals, polymers and woods. The de- vice of the invention is particularly useful in various immuno- assays using a solid support for separation of phases.

382046

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