Glaucoma-associated protein and corresponding nucleic acid...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 31/70 (2006.01) A61K 39/395 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2271235

Diagnostics for glaucoma, which are based on detection of non-wildtype GLC1A genes or proteins in a subject, glaucoma therapeutics and assays for identifying agents that modulate the activity of GLC1A and that are therefore useful in treating or preventing glaucoma are described.

Agents utilisés pour le diagnostic du glaucome, ledit diagnostique étant fondé sur la détection de gènes ou de protéines GLC1A de type non sauvage chez un sujet; agents thérapeutiques pour lutter contre le glaucome; procédés de criblage pour identifier des agents qui modulent l'activité de GLC1A et sont donc utiles pour traiter ou prévenir le glaucome.

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