Glidobactin pf-1 peptide antitumor antibiotics

C - Chemistry – Metallurgy – 07 – D

Patent

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195/89, 530/5.06

C07D 245/02 (2006.01) A61K 31/395 (2006.01) A61K 38/05 (2006.01) C07K 5/02 (2006.01) C07K 5/062 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2031984

ABSTRACT Glidobactin PF-1 of the formula Image having antitumor activity is prepared by cultivation of Polyangium brachysporum in a nutient medium containing a suitable fatty acid ester, such as linolenate, together with other assimilable sources of carbon and nitrogen.

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