A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) C07K 16/30 (2006.01)
Patent
CA 2629125
The present invention provides novel antibodies that specifically bind to glycosylation-variant BEHAB isoforms, particularly human BEHAB, compositions and methods for producing such antibodies; methods and compositions comprising said antibodies for detecting malignant glioma in a mammal for differentially diagnosing malignant glioma from benign glioma, for monitoring malignant glioma tumor progression or regression and for treating malignant gliioma, and kits for detecting, diagnosing, monitoring and treating a glioma.
La présente invention concerne de nouveaux anticorps qui se lient spécifiquement à des isoformes BEHAB variables en fonction de la glycosylation, notamment à des BEHAB humains, des compositions et des procédés destinés à produire de tels anticorps ; des procédés et des compositions comprenant lesdits anticorps afin de détecter des gliomes malins chez un mammifère en vue de diagnostiquer de façon différentielle un gliome malin et un gliome bénin, en vue de surveiller la progression ou la régression du gliome malin et en vue de traiter un gliome malin, et des kits de détection, de diagnostic, de surveillance et de traitement d~un gliome.
Matthews Russell T.
Viapiano Mariano S.
Smart & Biggar
Yale University
LandOfFree
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